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Meldonium may be used to treat coronary artery disease.These heart problems may sometimes lead to ischemia, a condition where too little blood flows to the organs in the body, especially the heart. Because this drug is thought to expand the arteries, it helps to increase the blood flow as well as increase the flow of oxygen throughout the body. Meldonium has also been found to induce anticonvulsant and antihypnotic effects involving alpha 2-adrenergic receptors as well as nitric oxide-dependent mechanisms. This, in summary, shows that meldonium given in acute doses could be beneficial for the treatment of seizures and alcohol intoxication. It may also have some effect on decreasing the severity of withdrawal symptoms caused by the cessation of chronic alcohol use.

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Mildronate 500 mg Oral Contraindications: Do not take if: You have kidney disease. You have liver problems. Take other medicines that affect your liver. You are pregnant or plan to become pregnant. Use is not recommended for: People aged 65 and over. Children younger than 5 years. People with a history of stroke or traumatic brain injury. People with high blood pressure. People with diabetes, high blood sugar (diabetes mellitus), or heart problems. People with liver or kidney disease. People who recently used an antidepressant or antimanic medication. People with high blood pressure, kidney disease, or severe heart failure. Do not take if: You are breastfeeding, planning to breastfeed, or have breastfed within the past four weeks. You are taking a medication that contains: Caffeine (coffee, Mildronate 250 cola, energy drinks) Dextroamphetamine (amphetamine) Dimethylamylamine (DMAA) Ethylmorphine (Syrup of morphine) Inhaled ephedrine (Chantix) Inhaled nicotine (Nicotine patches, gum, lozenge, nasal spray, spray plus inhaler) Inhaled thioridazine (Tegretol) Inhaled tramadol (Ultram) Phenylpropanolamine (Dianabol, Epidolex) Stimulants that may affect this medicine include methylphenidate (Ritalin, Metadate, Ritalin SR) and amphetamine (Adderall XR, Adderall XR Extended Release). Talk to your doctor before beginning a diet supplement. If you have taken an allergy or cold medication within two hours before taking this medicine, your doctor may want you to stop taking this medicine for 1 to 3 days until you feel well. Stimulants may affect other medicines that are used in the treatment of depression. Tell your doctor about all current medicines and any you start or stop using. This medicine may affect other medicines that are used in the treatment of depression. Tell your doctor about all current medicines and any you start or stop using. Talk to your doctor or pharmacist if you are not sure whether this medicine is right for you. This medicine is not approved for use by anyone other than a health professional. If you should stop taking this or any other antidepressant antimanic medication, your doctor may try to prescribe another antidepressant or antimanic medication that you can take along with this medicine. This medicine contains ingredients that may cause allergy or sensitivity in some people. If you are allergic to any of the ingredients in this medicine, report your reaction to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. This medicine contains ingredients that may cause skin irritation. Avoid contact with the skin for at least 1 hour after application. You have a one-time chance of developing an allergy to this medicine called leukotriene-associated protein 1 drugstore coupon hair (LAPP-1). Tell your doctor if you have ever had a skin reaction to this medicine (e.g., hives, itching, rash, contact dermatitis, or photosensitivity). If you have severe stomach pain or cramping caused by a blockage of vein or artery, try giving this medicine at a different time of day or in a different quantity. Avoid use in patients with:.



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